Table 2.
Cross-correlations between iFISH, high-dose therapy use, age and ISS stage
| Factor | ISS I | ISS II | ISS III | P-value |
|---|---|---|---|---|
| Deletion 13 by FISH | 328/750 (44%) | 517/1055 (49%) | 414/814 (51%) | 0.014 |
| t(4;14) | 100/744 (13%) | 194/1037 (19%) | 139/803 (17%) | 0.012 |
| Deletion 17 by FISH | 79/738 (11%) | 134/997 (13%) | 110/793 (14%) | 0.129 |
| HD therapy with transplant (HDM) | 650/759 (86%) | 746/1062 (70%) | 531/821 (65%) | < 0.001 |
| Age ≥65 years | 174/759 (23%) | 358/1062 (34%) | 268/821 (33%) | < 0.001 |
Abbreviations: HD, high dose; HDM, high-dose melphalan; iFISH, fluorescent in situ hybridization; ISS, International Staging System; n/N (%): n, number with factor, N, number with valid data for factor; N/A: all positive or all negative for factor; P-value not available. Fisher exact test, otherwise χ2 test.