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. 2014 Apr 1;9(4):e93469. doi: 10.1371/journal.pone.0093469

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© 2014 Fullár et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Representative pictures of the macroscopic appearance of WT and Matn2^-/- DEN-treated mouse livers. 10 months after DEN exposure the number and size of macroscopic tumors were greater in Matn2^-/- than in WT livers (A). The number of tumors/animal (B) and the tumor volume (C) were significantly higher in Matn2^-/- mice compared to WT mice after DEN-treatment (n = 9 for WT DEN, n = 13 for Matn2^-/- DEN, **p<0.01).