Table 1. Differences between WT control and Matn2-/- control group compared to WT control.
Total protein | Phosphorylation | Immunostaining | Localization | |
EGFR | - | ↑ | - | - |
Erk1/2 | ↑↑↑ | ↑↑↑ | ↑↑ | cytoplasm, nucleus |
GSK-3α/β | ↑ | ↑↑ | ↑ | cytoplasm |
β-Catenin | ↑ | - | ↑ | cytoplasm |
c-Myc | - | ↓ (inactivating) | - | cytoplasm, nucleus |
p21/CIP1 | ↓ | - | ↓ | nucleus |
Ki-67 | - | - | ↑ | nucleus |
Rb | - | ↑ | ↑↑ | nucleus |