Table 3. Differences between Matn2-/- control and Matn2-/- DEN group compared to Matn2-/- control.
Total protein | Phosphorylation | Immunostaining | Localization | |
EGFR | - | ↑ | - | - |
Erk1/2 | ↑ | ↑ | ↑ = | cytoplasm, nucleus |
GSK-3α/β | ↑ | ↓ | = ↓ | cytoplasm |
β-Catenin | ↓ | - | ↑ | cytoplasm |
c-Myc | - | ↓ | - | cytoplasm, nucleus |
p21/CIP1 | ↑ | - | ↑ | nucleus |
Ki-67 | - | - | ↑↑↑ | nucleus |
Rb | - | = ↑ | = | nucleus |