Table 4. Reduction of testis weights and sperm counts in 8-week-old 129S1/SvImJ mice exposed to cyclophosphamide (CP) in utero.
Treatment | Testis weight (mg) | Sperm head count/testis | Sperm count/cauda epididymis |
Control (n = 5) | 97±2 | 29 (±2) × 106 | 10.2 (±0.8) × 106 |
CP (n = 4) | 75±1 a | 18 (±2) × 106 a | 7.1 (±0.5) × 106 a |
Significantly different between treated and control mice (P<0.01; t-test).