Table 1. Systemic application of clodrolip decreases the numbers of macrophages in the skin.
| BCC-bearing skin | ||||
| mouse | Mac1+ | F4/80+ | Mac1+F4/80+ | |
| liposomes | M1 | 5.98 | 4.30 | 4.40 |
| M2 | 4.97 | 4.82 | 3.57 | |
| M3 | 3.02 | 3.77 | 2.52 | |
| mean (SEM) | 4.66 (0.87) | 4.30 (0.30) | 3.50 (0.54) | |
| clodrolip | M1 | 4.69 | 2.41 | 2.38 |
| M2 | 1.00 | 0.82 | 0.64 | |
| M3 | 1.74 | 0.96 | 0.85 | |
| mean (SEM) | 2.48 (1.13) | 1.40 (0.51) | 1.29 (0.55) | |
The percentage of Mac1+, F4/80+ and Mac1+F4/80+ double-positive cells in tumor-bearing skin of Ptchflox/floxERT2+/− mice was determined by FACS. M1 to M3: mouse 1 to mouse 3.