Table 1. Summary of electrophysiology parameters for Figures 5–8.
Figure 5 and 7. Voltage-sensitivities of LCav1, LCav2, LCav3 channels with and without LCavβ splice isoforms | ||||||||||||
Activation V0.5 (mV) | p value | Activation Ka | n | p value | Inactivation V0.5 (mV) | n | p value | Inactivation Ki | n | p value | ||
LCav1 & no β | 3.27±4.27 | 8 | 7.83±1.50 | 8 | −20.29±4.56 | 3 | 8.30±1.72 | 3 | ||||
LCav1 & LCavβA+ | 2.07±1.05 | 7 | n.s. | 7.09±1.21 | 7 | n.s. | −16.47±4.27 | 3 | n.s. | 7.56±1.50 | 3 | n.s. |
LCav1 & LCavβB+ | 2.47±1.03 | 24 | n.s. | 6.77±0.76 | 24 | n.s. | −21.33±2.18 | 5 | n.s. | 8.57±1.69 | 5 | n.s. |
LCav1 & LCavβB− | 3.55±1.57 | 5 | n.s. | 6.96±1.74 | 5 | n.s. | −18.09±3.72 | 3 | n.s. | 8.25±1.45 | 3 | n.s. |
LCav2 & no β | 12.11±2.20 | 5 | 6.43±1.91 | 5 | −31.28±6.76 | 4 | 10.90±1.21 | 4 | ||||
LCav2 & LCavβA+ | 12.30±0.96 | 10 | n.s. | 6.74±0.27 | 10 | n.s. | −29.18±2.32 | 7 | n.s. | 11.02±1.63 | 7 | n.s. |
LCav2 & LCavβB+ | 12.07±1.21 | 8 | n.s. | 6.49±1.74 | 8 | n.s. | −33.02±3.20 | 4 | n.s. | 9.15±2.01 | 4 | n.s. |
LCav2 & LCavβB− | 9.95±1.07 | 5 | * | 6.13±0.30 | 5 | n.s. | −32.37±2.57 | 4 | n.s. | 9.26±1.21 | 4 | n.s. |
LCav3 & no β | −67.65±1.20 | 9 | 4.68±0.20 | 9 | −84.12±0.38 | 3 | 3.16±0.15 | 3 | ||||
LCav3 & LCavβA+ | −68.71±2.69 | 10 | n.s. | 4.64±0.61 | 10 | n.s. | −84.82±1.19 | 3 | n.s. | 3.28±0.24 | 3 | n.s. |