Figure 8. Increased atherosclerotic lesion formation in Ldlr^−/−Pd1^−/− mice.

a) Representative images and quantitative analysis of atherosclerotic lesion size in the aortic sinus of Ldlr ^−/− or Ldlr ^−/− Pd1 ^−/− mice after 9 weeks of high fat diet feeding. b) Representative images of Oil-Red-O stained aortae and quantitative analysis of atherosclerotic lesion size in the aorta of Ldlr ^−/− or Ldlr ^−/− Pd1 ^−/− mice after 9 weeks of high fat diet feeding (n = 8–10/group). (c) Quantitative analysis of Mac2⁺ monocyte/macrophage numbers and frequencies among total plaque cells in the aortic sinus of Ldlr^−/− and Ldlr^−/−Pd1^−/− mice after 9 weeks of high fat diet feeding (n = 5–9/group). *p<0.05 **p<0.01 ***p<0.001.