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. 2014 Apr 1;9(4):e93477. doi: 10.1371/journal.pone.0093477

Figure 1. Serotype distribution of Streptococcus pneumoniae was analyzed regarding preceding respiratory viral infections and influenza epidemic periods.

Figure 1

(A) Serotype distribution of Streptococcus pneumoniae in terms of preceding respiratory viral infections among patients with pneumonia. ICI serotypes (4, 5, 7F/7A, 8, 9V/9A, 12F and 18C) were more likely to cause post-viral pneumococcal pneumonia compared to other serotypes (*P<0.05). (B) Serotype distribution of Streptococcus pneumoniae in terms of influenza epidemic periods among patients with pneumonia. ICI serotypes were more likely to cause pneumococcal pneumonia during influenza epidemic periods, while serotype 6B was more common during non-epidemic periods (*P<0.05). ICI, infrequently colonizing but invasive serotypes; FCI, frequently colonizing and invasive serotypes; FCWI, frequently colonizing but weakly invasive serotypes; NT, non-typeable.