Table 2. Independent risk of recipients with UGT1A1*28 polymorphism 6/7+7/7 versus 6/6 of acute rejection analyzed by multivariate logistic regression.
Odds ratio | 95% confidence interval | P value | |
HO-1 (A-413T) TT + AT vs. AA | |||
Model 1a | 0.81 | 0.47–1.39 | 0.436 |
Model 2b | 0.76 | 0.44–1.33 | 0.340 |
Model 3c | 0.88 | 0.47–1.68 | 0.707 |
UGT1A1*28 6/7+7/7 vs. 6/6 | |||
Model 1a | 0.44 | 0.25–0.76 | 0.004 |
Model 2b | 0.34 | 0.19–0.63 | 0.001 |
Model 3c | 0.22 | 0.09–0.53 | 0.001 |
adjusted for recipient age and recipient gender; badjusted for recipient age, recipient gender, number of HLA mismatches, donor type; cadjusted for recipient age, recipient gender, number of HLA mismatches, donor type, number of transplantations, type of calcineurin inhibitor, hypertension and diabetes mellitus.