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. 2014 Apr 1;9(4):e93633. doi: 10.1371/journal.pone.0093633

Table 2. Independent risk of recipients with UGT1A1*28 polymorphism 6/7+7/7 versus 6/6 of acute rejection analyzed by multivariate logistic regression.

Odds ratio 95% confidence interval P value
HO-1 (A-413T) TT + AT vs. AA
Model 1a 0.81 0.47–1.39 0.436
Model 2b 0.76 0.44–1.33 0.340
Model 3c 0.88 0.47–1.68 0.707
UGT1A1*28 6/7+7/7 vs. 6/6
Model 1a 0.44 0.25–0.76 0.004
Model 2b 0.34 0.19–0.63 0.001
Model 3c 0.22 0.09–0.53 0.001
a

adjusted for recipient age and recipient gender; badjusted for recipient age, recipient gender, number of HLA mismatches, donor type; cadjusted for recipient age, recipient gender, number of HLA mismatches, donor type, number of transplantations, type of calcineurin inhibitor, hypertension and diabetes mellitus.