Table 1. Clinical and Molecular Characteristics of the 83 GBM Patients*.
Clinical or MolecularFeature | Cases | ||
No. | % | ||
Total No. of patients | 83 | ||
Sex | |||
Male | 50 | 60.2 | |
Female | 33 | 39.8 | |
Age, years | |||
Mean | 56.7 | ||
SD | 17.8 | ||
≥60 | 40 | 48.2 | |
<60 | 43 | 51.8 | |
KPS | |||
Mean | 78.7 | ||
SD | 12.4 | ||
Tumor size, cm3 | |||
Mean | 66.8 | ||
SD | 24.2 | ||
Extent of resection | |||
Gross total resection | 38 | 45.8% | |
Residual tumor <30% | 20 | 24.1% | |
Residual tumor >30% | 25 | 30.1% | |
MGMT promoter | |||
Methylated | 25 | 30.1% | |
Unmethylated | 58 | 69.9% | |
Plasma IGFBP-2, ng/ml | |||
Mean | 637.0 | ||
SD | 52.3 | ||
Median | 627.5 |
*KPS: Karnofsky performance status; IGFBP-2: Insulin-like growth factor binding protein 2; MGMT: O(6)-methylguanine-DNA-methyltransferase.