Figure 5.
Assessment of the effects of (+)-naltrexone on SNAP. Rats were tested for mechanical allodynia across a timecourse on both the ipsilateral (A) and contralateral (B) hindpaw. Rats that received (+)-naltrexone (6 mg/kg, s.c.) for 14 days beginning 32 days after surgery were significantly less allodynic than rats that received vehicle in both the ipsilateral (C) and contralateral (D) hindpaw. Data are presented as mean ± SEM and analyzed using a one-way ANOVA on the AUCs, n=6 per group. *p<0.05 compared to all other groups.
