Table 3.
Separate Multivariable Linear Regression Models for each Measure of Nerve Function and Muscle Power (watts/kg)
| 1st Models | 2nd Models | 3rd Models | 4th Models | ||||
|---|---|---|---|---|---|---|---|
| β (SE) | β (SE) | Attenuated by | β (SE) | Attenuated by | β (SE) | Attenuated by | |
| Motor nerve function per SD lower | |||||||
| Motor amplitude | −0.10‡ (0.03) | −0.07* (0.03) | Fat mass | −0.08* (0.03) | Muscle density | −0.07* (0.03) | Fat mass |
| Distal motor latency | −0.05 (0.03) | −0.04 (0.03) | −0.04 (0.03) | −0.05 (0.03) | |||
| Mean F-wave latency | 0.05 (0.03) | 0.05 (0.03) | 0.05 (0.04) | 0.06 (004) | |||
| Sensory nerve function per SD lower | |||||||
| Sensory amplitude | −0.10‡ (0.04) | −0.09* (0.04) | Fat mass | −0.09* (0.04) | Muscle density | −0.09* (0.04) | Fat mass |
| Distal sensory latency | −0.10 (0.34) | −0.06 (0.32) | −0.21 (0.34) | −0.10 (0.32) | |||
| Monofilament insensitivity (yes/no) | |||||||
| 1.4-g | −0.10 (0.06) | −0.11* (0.05) | −0.07 (0.06) | Muscle density | −0.12* (0.03) | ||
| 10-g | −0.16* (0.07) | −0.17* (0.07) | −0.12 (0.07) | Muscle density | −0.16* (0.03) | ||
| Neuropathic symptoms (yes/no) | |||||||
| Numbness | −0.10 (0.06) | −0.09 (0.06) | −0.10 (0.06) | −0.07 (0.06) | |||
| Pain | 0.01 (0.07) | 0.04 (0.07) | 0.07 (0.07) | 0.04 (0.07) | |||
| Open sore | −0.32 (0.18) | −0.36* (0.18) | −0.11 (0.19) | −0.34* (0.21) | |||
1st Models adjusted for age and height; 2nd Models adjusted for variables in 1st Models plus total body lean and fat mass; 3nd Models adjusted for variables in 1st Models plus muscle density and muscle cross-sectional area; 4nd Models adjusted for variables in 2st Models plus diabetes and hypertension; p>0.1 for AAI, CVD, CBVD, osteoarthritis, hip pain, smoking, alcohol use, physical activity, and cognitive function
*
p<0.05
†p<0.01
‡
p<0.001.