FIG 1.
Two-dimensional heat maps of TCRβ V-J use (percentage of different V-J pairing in total annotated TCRβ sequence reads from each group) for CD4+ T cells from healthy control subjects (n = 4), patients with atypical SCID (n = 2), patients with OS caused by non-RAG mutations (n = 2), and patients with OS caused by a RAG mutation (n = 5). The different Vβ genes are on the longitudinal ordinate, and the different Jβ genes are on the horizontal ordinate. P values of unpaired t tests are shown as follows: *.01 < P < .05, **.001 < P < .01, and ***P < .001. ns, Nonsignificant.