. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: Clin Trials. 2013 Oct 3;11(2):246–262. doi: 10.1177/1740774513498322

Table 2. Population Averaged Event Rate Estimates under Fixed RR and RD Assumptions.

	Event Rates	Treatment A	Treatment B	Treatment C
I. Fixed RR	True	0.25	0.375	0.50
	Observed data	0.25(0.19,0.34)	0.37(0.28,0.46)	0.50(0.38,0.61)
	Full data	0.25(0.19,0.31)	0.37(0.29,0.45)	0.50(0.38,0.59)
II. Fixed RD	True	0.25	0.40	0.50
	Observed data	0.24(0.18,0.33)	0.40(0.33,0.48)	0.50(0.43,0.57)
	Full data	0.25(0.19,0.32)	0.40(0.34,0.46)	0.50(0.43,0.56)

Results based on the proposed method; OR = Odds Ratio; RR = Relative Risk; RD = Rate Difference.