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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Clin Trials. 2013 Oct 3;11(2):246–262. doi: 10.1177/1740774513498322

Table 3. Relative Treatment Effects Estimates under Fixed RR and RD.

Observed Data Full Data
B vs. A C vs. A C vs. B B vs. A C vs. A C vs. B
I. Fixed RR
OR Peto 1.63 (1.50,1.77) 3.06 (2.74,3.41) 1.93 (1.75,2.13) 1.83 (1.74,1.93) 3.36 (3.13,3.61) 1.78 (1.67,1.90)
HOM* 1.60 (1.39,1.81) 3.18 (2.75,3.64) 1.99 (1.73,2.31) 1.87 (1.66,2.09) 3.29 (2.89,3.71) 1.76 (1.50,2.06)
ID# 1.66 (1.44,1.85) 3.23 (2.66,4.07) 1.98 (1.56,2.44) 1.88 (1.75,2.00) 3.30 (2.78,3.90) 1.76 (1.48,2.09)
New§ 1.72 (1.29,2.30) 2.97 (2.20,4.12) 1.74 (1.34,2.24) 1.78 (1.52,2.09) 2.96 (2.38,3.63) 1.66 (1.40,1.96)
RR True 1.50 2.00 1.33 1.50 2.00 1.33
New§ 1.45 (1.18,1.78) 1.98 (1.63,2.41) 1.36 (1.19,1.57) 1.49 (1.34,1.66) 1.98 (1.77,2.21) 1.33 (1.22,1.45)
II. Fixed RD
OR Peto 2.20 (2.03,2.37) 3.45 (3.10,3.83) 1.54 (1.41,1.69) 1.99 (1.89,2.09) 3.23 (3.01,3.46) 1.53 (1.44,1.63)
HOM* 2.28 (2.08,2.54) 3.36 (3.03,3.76) 1.47 (1.32,1.63) 2.06 (1.94,2.20) 3.15 (2.92,3.41) 1.53 (1.42,1.65)
ID# 2.31 (2.07,2.59) 3.40 (3.00,3.93) 1.47 (1.30,1.66) 2.07 (1.94,2.21) 3.16 (2.91,3.42) 1.53 (1.41,1.66)
New§ 2.09 (1.48,2.85) 3.17 (2.28,4.31) 1.52 (1.19,1.95) 1.99 (1.66,2.36) 2.98 (2.44,3.59) 1.50 (1.28,1.75)
RD True 0.15 0.25 0.10 0.15 0.25 0.10
New§ 0.16 (0.09,0.22) 0.26 (0.19,0.32) 0.10 (0.04,0.16) 0.15 (0.11,0.18) 0.25 (0.21,0.28) 0.10 (0.06,0.14)
*

The contrast-based NMA with a homogeneous variance assumption

#

The contrast-based NMA with an unstructured heterogeneous variance assumption

§

The proposed arm-based NMA with an unstructured heterogeneous variance assumption

OR = Odds Ratio; RR = Relative Risk; RD = Rate Difference;