Table 3. Relative Treatment Effects Estimates under Fixed RR and RD.
Observed Data | Full Data | ||||||
---|---|---|---|---|---|---|---|
B vs. A | C vs. A | C vs. B | B vs. A | C vs. A | C vs. B | ||
I. Fixed RR | |||||||
OR | Peto | 1.63 (1.50,1.77) | 3.06 (2.74,3.41) | 1.93 (1.75,2.13) | 1.83 (1.74,1.93) | 3.36 (3.13,3.61) | 1.78 (1.67,1.90) |
HOM* | 1.60 (1.39,1.81) | 3.18 (2.75,3.64) | 1.99 (1.73,2.31) | 1.87 (1.66,2.09) | 3.29 (2.89,3.71) | 1.76 (1.50,2.06) | |
ID# | 1.66 (1.44,1.85) | 3.23 (2.66,4.07) | 1.98 (1.56,2.44) | 1.88 (1.75,2.00) | 3.30 (2.78,3.90) | 1.76 (1.48,2.09) | |
New§ | 1.72 (1.29,2.30) | 2.97 (2.20,4.12) | 1.74 (1.34,2.24) | 1.78 (1.52,2.09) | 2.96 (2.38,3.63) | 1.66 (1.40,1.96) | |
RR | True | 1.50 | 2.00 | 1.33 | 1.50 | 2.00 | 1.33 |
New§ | 1.45 (1.18,1.78) | 1.98 (1.63,2.41) | 1.36 (1.19,1.57) | 1.49 (1.34,1.66) | 1.98 (1.77,2.21) | 1.33 (1.22,1.45) | |
II. Fixed RD | |||||||
OR | Peto | 2.20 (2.03,2.37) | 3.45 (3.10,3.83) | 1.54 (1.41,1.69) | 1.99 (1.89,2.09) | 3.23 (3.01,3.46) | 1.53 (1.44,1.63) |
HOM* | 2.28 (2.08,2.54) | 3.36 (3.03,3.76) | 1.47 (1.32,1.63) | 2.06 (1.94,2.20) | 3.15 (2.92,3.41) | 1.53 (1.42,1.65) | |
ID# | 2.31 (2.07,2.59) | 3.40 (3.00,3.93) | 1.47 (1.30,1.66) | 2.07 (1.94,2.21) | 3.16 (2.91,3.42) | 1.53 (1.41,1.66) | |
New§ | 2.09 (1.48,2.85) | 3.17 (2.28,4.31) | 1.52 (1.19,1.95) | 1.99 (1.66,2.36) | 2.98 (2.44,3.59) | 1.50 (1.28,1.75) | |
RD | True | 0.15 | 0.25 | 0.10 | 0.15 | 0.25 | 0.10 |
New§ | 0.16 (0.09,0.22) | 0.26 (0.19,0.32) | 0.10 (0.04,0.16) | 0.15 (0.11,0.18) | 0.25 (0.21,0.28) | 0.10 (0.06,0.14) |
The contrast-based NMA with a homogeneous variance assumption
The contrast-based NMA with an unstructured heterogeneous variance assumption
The proposed arm-based NMA with an unstructured heterogeneous variance assumption
OR = Odds Ratio; RR = Relative Risk; RD = Rate Difference;