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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Kidney Int. 2013 Nov 27;85(4):845–854. doi: 10.1038/ki.2013.488

Figure 3. Effect of periostin expression on renal cyst development in pcy/pcy mice.

Figure 3

(a) Representative kidney sections of male pcy/pcy: Postn+/+ and pcy/pcy: Postn−/− mice. Scale bar is 1 mm. (b) Cross-sectional surface area of cysts is represented as % of total area minus the area of the renal pelvis. Data are mean ± SE from three representative sections per kidney. pcy/pcy: Postn−/− kidneys had a marked reduction in cystic area compared to pcy/pcy: Postn+/+ kidneys. (c) The number of cysts (≥ 50 μm) per section was also significantly reduced in the pcy/pcy: Postn−/− kidneys (190 ± 30 vs. 265 ± 15). Data are means ± SE. Statistical analysis was determined by an unpaired t-test. *P < 0.05, compared to the pcy/pcy: Postn+/+ kidneys.