Table 1.
Demographics, ejaculated sperm characteristics, and testicular germ cell populations by testicular histology type of the 43 men included in the analysis. All values are expressed as median (25th, 75th percentiles).
| Testicular Histology | |||||
|---|---|---|---|---|---|
| Normal† (n=11) |
Sertoli-Cell Only (n=20) |
Maturation Arrest (n=8) |
Hypospermatogenesis (n=4) |
p-value | |
| Age (years) | 30 (29,37) | 35 (32,39) | 31 (29,33) | 35 (31,37) | .32 |
| Sperm Characteristics | |||||
| Semen Volume (ml) | 1.8 (0.5,2.7)** | 3 (2.5, 3.0) | 4 (3.8,4.8) | 2.5 (0.7,6) | .01 |
| Sperm Concentration (106/ml ejaculate) | 0 (0,0.2) | 0 (0,0) | 0 (0,0.01) | 0 (0,0) | .25 |
| Total Sperm Count (106/ejaculate) | 0 (0,0.3) | 0 (0,0) | 0 (0,0.04) | 0 (0,0) | .15 |
| Germ Cell Populations (per tubule cross-section) | |||||
| Spermatogonia | 11 (9,14) | 0 (0,0)** | 16 (10,18)* | 6.8 (6.7, 7.0) | 0.001 |
| Spermatocytes | 14 (13,15) | 0 (0,0)** | 19 (14,29)* | 5.2 (4.9,8.6) | 0.001 |
| Spermatids (type a+ type b) | 9 (5,13)* | 0 (0,0)** | 1.5 (0.3,2.5) | 3.1 (0.8,4.4) | 0.001 |
| Spermatids (type c+ type d) | 8 (7,9)* | 0 (0,0)** | 0 (0,0.9) | 0.8 (0.7,1.6) | 0.001 |
Nine of these men had obstructive azoospermia.
p<0.01 c.f. other groups;
p<0.05 c.f. other groups