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. Author manuscript; available in PMC: 2015 Apr 17.
Published in final edited form as: Neurosci Lett. 2013 Nov 19;0:53–58. doi: 10.1016/j.neulet.2013.11.015

Figure 1.

Figure 1

Effect of miR-181a and miR-29a on focal and global cerebral ischemia. A. Representative cresyl violet-stained coronal sections demonstrate a decreased infarct size in miR-181a down-regulated brain compared with brain treated with miR-181 mismatch (Ctrl) subjected to 1 h MCAO and 48 h reperfusion. The bar graph shows quantitation of infarct size (modified from Fig. 5 in [42]). B. Representative cresyl violet-stained coronal hippocampal sections demonstrate selective loss of CA1 neurons (between white arrows) at 6 days reperfusion after 10 min forebrain ischemia in control ischemic animals and protection with miR-29a overexpression. Quantitation of CA1 neuronal loss is shown in the bar graph (modified from Fig. 6 in [46]).