Table 1.
Parameter | Values |
---|---|
Number (n) | 22 |
Age (years) | 32.1 (13.6) |
Gender (M / F) | 14 / 8 |
FEV1 (% predicted) | 56 (21) |
Body weight (kg) | 63.9 (11.9) |
dF508 heterozygote (%) | 100 |
dF508 homozygote (%) | 77 |
CF-related diabetes (%) | 68 |
Hemoglobin (gm/dl)* | 13.6 (0.9) (men) 12.6 (0.7) (women) |
Serum iron (µg/dl)** | 62 (38) (men) 51 (22) (women) |
TSAT (%)* | 13 (5) (men) 10 (4) (women) |
Serum hepcidin-25 (ng/ml)** | 48.6 (41.9) |
Sputum iron (ng/mg)**, † | 1.44 (1.0) |
Data are presented as mean (standard deviation) unless otherwise noted.
Measured at screening
Measured at randomization
Based on sputum samples collected from 21 of 22 subjects.