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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pflugers Arch. 2013 Oct 1;466(7):1289–1300. doi: 10.1007/s00424-013-1358-1

Figure 5. Single-channel properties of THIK-1.

Figure 5

A. Tracings show currents from cell-attached patches from untransfected cells and cells transfected with plasmid containing GFP and/or THIK-1 DNA. Cells transfected with THIK-1 DNA show low amplitude channel openings indicated by dotted lines.

B. Currents were recorded from inside-out patches held at various membrane potentials as indicated.

C. Plot shows an amplitude histogram of channel openings recorded at +100 mV (pipette potential). The histogram was fitted with a Gaussian curve.

D. Plot shows a single-channel current-voltage relationship of THIK-1.

E. Plot shows changes in reversal potential (Erev) at different [K+]o. Experimental and theoretical (Nernst Equation) data are shown.