Table 2.

Relation of baseline amino acid levels and the development of hypertriglyceridemia after 7 years

Amino acid levels at baseline	Model 1	Model 2	Model 3	Model 4
Arginine	0.009	0.012	0.009	0.017
Leucine	0.001	0.022	0.010	0.018
Valine	8.2 × 10 −4	0.021	0.013	0.027
Proline	0.002	0.008	0.017	0.029
Phenylalanine	0.009	0.057	0.021	0.038
Isoleucine	9.4 × 10 −4	0.049	0.033	0.054
Lysine	0.022	0.073	0.042	0.069
Aspartic acid	0.094	0.21	0.11	0.13
Serine	0.24	0.15	0.12	0.17
Ornithine	0.11	0.20	0.14	0.19
Glutamine	0.31	0.19	0.16	0.20
Tyrosine	0.10	0.39	0.21	0.28
Methionine	0.16	0.47	0.31	0.32
Histidine	0.41	0.67	0.41	0.50
Asparagine	0.91	0.51	0.48	0.50
Glutamic acid	0.071	0.34	0.33	0.54
Citrulline	0.58	0.55	0.71	0.54
Glycine	0.87	0.81	0.72	0.69
Threonine	0.86	0.71	0.73	0.69
Tryptophan	0.47	0.90	0.67	0.81
Alanine	0.60	0.72	0.70	0.84

n = 755 (121 cases) for model 1 + 2; n = 686 (103 cases) for model 3

Values represent p values for logistic regression analyses for the risk of developing hypertriglyceridemia (>1.70 mmol/L). All amino acid levels were log-transformed

Values in bold are significant at p < 0.05

Model 1: adjusted for gender, age and body mass index at baseline

Model 2: adjusted for gender, age, body mass index and triglyceride levels at baseline

Model 3: adjusted for gender, age, body mass index and triglyceride levels at baseline and restricted to non-diabetic subjects (both at baseline and at 7 years)

Model 4: adjusted for gender, age, body mass index, triglyceride and hexose levels at baseline and restricted to non-diabetic subjects (both at baseline and at 7 years)