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. 2014 Mar 26;8:23. doi: 10.3389/fncir.2014.00023

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Copyright © 2014 Liu, Wang and Cang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Disrupted receptive field structures in the SC of ephrin-A knockout mice. (A,B) Receptive field of a SC neuron in WT mouse. A shows peri-stimulus timing histograms (PSTH) in response to spots flashed at different locations on a 13 × 13 grid in visual space. Scale bars are 50 spikes/s (y-axis, for firing rate in each 50 ms bin) and 1 s (x-axis). Both On and Off responses were evoked within the receptive field, as indicated by the two peaks in individual PSTHs. The receptive field structure determined by the PSTHs is shown in B in a color scale (right, in spikes/s, for mean firing rate in the 1 s stimulus duration). (C–H) Example receptive fields of SC neurons in ephrin-A double (DKO) and triple KO (TKO) mice.