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. 2014 Mar 26;5:123. doi: 10.3389/fimmu.2014.00123

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Copyright © 2014 Li and Mariuzza.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Structures of NKG2D and NKG2A/CD94 complexes. (A) The human NKG2D–MICA complex (1HYR). The two subunits of the NKG2D homodimer are cyan; MICA is yellow. (B) The mouse NKG2D–RAE-1β complex (1JSK). (C) The human NKG2D–ULBP3 complex (1KCG). (D) Structure of the MCMV immunoevasin m152 bound to the NKG2D ligand RAE-1γ (4G59). (E) Structure of the Ig-like HCMV immunoevasin UL16 bound to MICA (2WY3). (F) The human NKG2A/CD94–HLA-E complex (3CDG). The NKG2A and CD94 subunits of the NKG2A/CD94 heterodimer are cyan and green, respectively.