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. 2014 Mar 26;5:123. doi: 10.3389/fimmu.2014.00123

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Copyright © 2014 Li and Mariuzza.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interaction of LILRB1 with MHC-I and a viral MHC-I mimic. (A) Structure of LILRB1 bound to HLA-A2 (1P7Q). The α1, α2, and α3 domains of the HLA-A2 heavy chain are yellow; β₂m is gray; the peptide is magenta. The D1 and D2 domains of LILRB1 are colored in cyan and green, respectively. The secondary structural elements of LILRB1 are labeled. (B) Structure of LILRB1 bound to the HCMV MHC-I mimic UL18 (3D2U).