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. 2014 Mar 26;5:123. doi: 10.3389/fimmu.2014.00123

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Copyright © 2014 Li and Mariuzza.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Natural cytotoxicity receptors. (A) Structure of NKp44 (1HKF). The β-strands are labeled. The CC′ and FG loops, drawn in red, define a positively charged surface groove that may serve as a binding site for anionic ligands. (B) Structure of NKp46 (1P6F). D1 is cyan; D2 is green. (C) Structure of NKp30 bound to its tumor cell ligand B7-H6 (3PV6). N-linked glycans at B7-H6 residues Asn43 and Asn57 in the V-like domain and Asn208 in the C-like domain are shown in ball-and-stick representation.