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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Immunol. 2014 Mar 3;192(7):2970–2974. doi: 10.4049/jimmunol.1302678

Figure 4.

Figure 4

Resistance against Foxp3 expression among maternal CD4+ T cells causes antigen specific fetal loss in allogeneic pregnancy. Percent and number of 2W1S+ offspring per litter with (A) allogeneic pregnancy sired by 2W1S-expressing males on the Balb/c (H-2d) background or (B) syngeneic pregnancy sired by 2W1S-expressing males on the C57Bl/6 (H-2b) background among virgin C57Bl/6 females infected with the indicated recombinant Lm 60 days prior to mating. For some mice, CD4+ cells were depleted (anti-CD4) or IFN-γ neutralized (anti-IFN-γ) prior to mating. Each point reflects the data from a single mouse, and results combined from at least three independent experiments each with similar results are shown. Bar, mean ± one standard error.