Table 6.
Mean value (standard deviation) of Apoptosis index and ratio (standard deviation) of expression of inflammation and hypoxia markers according to plasmodial species infecting the placenta
| PM- a | PM + Pf a | PM + Pv a | PM + mixed | P* | |
|---|---|---|---|---|---|
|
Apoptotic cells index |
44.78 (2.15) |
71.32 (4.45) |
61.04 (5.96) |
57.56 (3.06) |
0.000 |
|
Fas |
3.2 (0.84) |
5.18 (2.11) |
6.57 (1.61) |
10.49 (2.09) |
0.000 |
|
FasL |
6.74 (1.16) |
4.49 (2.47) |
5.5 (2.82) |
5.68 (2.3) |
0.009 |
|
HIF |
0.1 (0.22) |
0.37 (0.66) |
0.35 (0.47) |
0.82 (2.97) |
0.000 |
|
VEGF |
0.05 (0.15) |
0.09 (0.17) |
0.06 (0.07) |
0.09 (0.06) |
0.412 |
|
COX1 |
0.43 (0.41) |
6.64 (3.54) |
5.22 (0.69) |
5.9 (3.4) |
0.000 |
| COX2 | 0.24 (0.29) | 2.45 (0.93) | 2.71 (0.82) | 2.19 (1.82) | 0.000 |
a PM- without placental malaria (n = 25); PM + Pf with placental infection by P. falciparum (n = 16); PM + Pv with placental infection by P. vivax (n = 6); PM + mixed with placental infection by both species (n = 3).
*(Kruskal-Wallis).