TABLE III.
Effect of Immobilized GAGs on Apoptotic Mk Fraction within the Megakaryocyte Population
| Apoptotic Mk Fraction (%) |
||||
|---|---|---|---|---|
| Culture Surface | Day 7 | Day 11 | Day 14 | Day 17 |
| Polystyrene control | 5.2 ± 0.2 | 26.3 ± 3.6 | 33.5 ± 4.1 | 46.3 ± 8.0 |
| Chitosan control | 5.2 ± 0.6 | 21.6 ± 3.3a | 33.2 ± 11.1 | 48.3 ± 8.0 |
| Heparin | 4.3 ± 0.5a | 21.5 ± 2.4a | 36.6 ± 13.3 | 55.2 ± 10.9 |
| Dermatan sulfate | 3.3 ± 0.9a,b | 19.9 ± 3.5a | 38.4 ± 12.2 | 56.8 ± 5.1 |
| Hyaluronan | 4.0 ± 0.3a,b | 20.1 ± 3.9a | 32.9 ± 7.8 | 56.2 ± 5.0 |
| Heparan sulfate | 4.1 ± 0.3a,b | 17.8 ± 2.6a | 45.6 ± 8.7a | 56.4 ± 4.7 |
a
Comparison with polystyrene surface, p < 0.05.
b
Comparison with chitosan surface, p < 0.05.