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(a) Rho-GTPase network (> 70 proteins): an actin-activating network that underpins a wide range of cytoskeletal activity: movement, adhesion, microtubules, nuclear separation etc. (b) the EGF network (> 60 proteins) activates the cell cycle. Note that these networks are not full graphs as the details of the interactions between the proteins (the “edges”) are not specified (from [20]).
