Table 2. Association of the degree of FI in the pancreas with pancreatic ductal adenocarcinoma.

	FI in the pancreas
	<10%		≥10%, <20%		≥20%
Population	OR	95% CI	OR	95% CI	OR	95% CI	Pa
All subjects
Cases/controls		17/30		21/25		64/30
Crude estimate	1	Reference	1.4	(0.6–3.4)	3.7	(1.8–7.8)	<0.001
Adjusted estimateb	1	Reference	2.3	(0.8–6.2)	6.1	(2.4–15.2)	<0.001
Excluding those with BMI of ≥25 kg/m2
Cases/controls		17/28		18/22		49/24
Adjusted estimatec	1	Reference	2.1	(0.7–5.9)	6.3	(2.4–16.5)	<0.001
Excluding those with past history of DM
Cases/controls		14/28		18/21		40/22
Adjusted estimated	1	Reference	3.1	(1.0–9.3)	7.5	(2.6–21.3)	<0.001
Excluding those with family history of PC
Cases/controls		15/29		17/25		59/30
Adjusted estimatee	1	Reference	2.0	(0.7–5.5)	5.4	(2.2–13.6)	<0.001

BMI, body mass index; CI, confidence interval; DM, diabetes mellitus; FI, fatty infiltration; OR, odds ratio; PC, pancreatic cancer.

^aStatistical tests for trend (two-sided) were assessed by assigning ordinal values to the degree of FI in the pancreas.

^bAdjusted for sex, age (≤60, 61–70 and >70), BMI (<25, ≥25), past history of DM (yes or no) and family history of PC (yes or no).

^cAdjusted for sex, age (≤60, 61–70 and >70), past history of DM (yes or no), and family history of PC (yes or no).

^dAdjusted for sex, age (≤60, 61–70 and >70), BMI (<25, ≥25), and family history of PC (yes or no).

^eAdjusted for sex, age (≤60, 61–70 and >70), BMI (<25, ≥25), and past history of DM (yes or no).