Figure 4.

ProHNPs, MPO, lysozyme, NGAL and PMNs in peripheral blood of two patients who underwent induction chemotherapy for AML. (a) Patient 35 in whom MPO and lysozyme increased early, possibly reflecting this patient's underlying myelodysplasia. The eventual rise of proHNPs was linked to reappearance of neutrophils in circulation. (b) Patient 38 in whom lysozyme increased early, most likely signifying reappearance of malignant myelopoiesis. AML, acute myeloid leukemia; HNP, human neutrophil peptides; MPO, myeloperoxidase; NGAL, neutrophil gelatinase-associated lipocalin; PMNs, polymorphonuclear neutrophils.