Table 3. Clinical data from patients who underwent chemotherapy for acute leukemias.
No. | Age | Sex | Diagnosis | Treatment | G-CSF | PPI | Peak proHNPs (μg/ml) |
---|---|---|---|---|---|---|---|
28 | 45 | F | AML | HD Cytosar | 3–5 | 7.7 | |
29 | 45 | F | AML | HD Cytosar | 4–6 | 4.5 | |
30 | 57 | M | ALL | Hyper-CVAD | Filgrastim 0.96 mg daily | 5 | 33.7 |
31 | 55 | F | AML | HD Cytosar | — | 16.2 | |
32 | 66 | F | AML | Da 3+10 | 3–5 | 20.2 | |
33 | 66 | F | AML | Da 3+8 | 2–5 | 20.4 | |
34 | 67 | M | AML | Da 3+10 | 4 | 28.8 | |
35 | 51 | M | AML | Da 3+10 | — | 0.98 | |
36 | 44 | F | AML | FLAG-IDA | Lenograstim 0.263 mg daily | 3–5 | 19.2 |
37 | 51 | M | AML | Da 3+10 | 5–7 | 18.1 | |
38 | 70 | M | AML | FLAG-Nov | Filgrastim 0.30 mg daily | — | 2.1 |
39 | 23 | M | AML | Da 3+10 | Pegfilgrastim 6 mg × 1 | 5–7 | 36.3 |
40 | 70 | M | AML | FLAG | Filgrastim 0.30 mg daily | 5 | 18.6 |
41 | 65 | M | AML | Da 3+10 | 7 | 24.1 |
Abbreviations: ALL, acute lymphoid leukemia; AML, acute myeloid leukemia; Da 3+8, daunorubicin, cytarabine; Da 3+10, daunorubicin, cytarabine; F, female; FLAG-Ida, fludarabine, cytarabine, lenograstim, idarubicin; FLAG-Nov, fludarabine, cytarabine, filgrastim, mitoxantron; G-CSF, granulocyte colony-stimulating factor; HD Cytosar, high-dose cytarabine; HNP, human neutrophil peptides; Hyper-CVAD, cyclophosphamid, vincristin, cytarabine, doxorubicin, intrathecal methotrexate; M, male; PPI, ProHNP-PMN-Interval.