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General immune effector cells are not affected by 5-Azacytidine treatment in vivo. The number and reactivity of NK cells and CD8 and CD4 T cells are shown. First cycle represents a sample obtained before treatment. (a, c, e) absolute peripheral blood counts of CD8 and CD4 T cells and CD3−CD56+CD16+/− NK cells, respectively. (b, d, f) Expression of CD107a on CD8 and CD4 T cells and NK cells, respectively, in response to SEB (for T cells) or to K562 cells (for NK cells).
