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Representative responses to forearm exercise with balloon-induced hypoperfusion under control (no drug; ●) and nitric oxide synthase (NOS) inhibition [NG-monomethyl-l-arginine (l-NMMA); ○] conditions. Circles at baseline (rest) represent 5-s FVC averages, whereas circles during exercise (20% MVC) represent FVC averages per duty cycle (1-s contraction and 2-s relaxation period). The vasodilation and related recovery of flow following balloon inflation were blunted by NOS inhibition.
