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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: Lab Chip. 2009 Oct 22;10(1):51–58. doi: 10.1039/b913221j

Table 1.

Oxygen consumption rates in the bioreactor compared with oxygen consumption in isolated hepatocytes and a perfused rat liver. To convert to equivalent units in all systems, we assumed 110 × 106 cells per gram of liver28 and 1 mg protein per 106 cells (observation from our laboratory).

µmol hour−1 mg protein−1 Periportal or
tissue inlet
Pericentral or
tissue outlet
Total
Perfused multiwell plate 4.7 1.8 2.6
Isolated hepatocytes29 2.5
Perfused rat liver30 1.8
Perfused rat liver31 1.2 0.6 1.0