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. 2014 Mar 5;2014:165897. doi: 10.1155/2014/165897

Table 2.

Differentially expressed microRNAs in retinal cell types.

MicroRNA Regulation/function Retinal cell type Refs
miR-204, miR-211 Upregulated RPE [48]
miR-23a Upregulated (in healthy cells)  
Downregulated (in AMD)
RPE [49]
miR-183/96/182 Downregulated in dark  
Upregulated in light
Photoreceptors and interneurons of the inner nuclear layer [36]
miR-29b Upregulated after streptozotocin (STZ) injection; upregulation protects against apoptosis RGCs and cells of the INL [47]
mir-133b Overexpression suppresses maturation and function of dopaminergic amacrine cells Dopaminergic amacrine cells [46]
mir-124 Abundantly expressed in differentiated neurons All retinal cell layers, but is not detected in the RPE [45]
miR-155*, miR-124. Resting microglia: low expression of miR-155 and high expression of miR-124  
Activation phenotype (M1): downregulation of miR-124, upregulation of miR-155  
Activation phenotype (M2): upregulation of miR-124, 
downregulation of miR-155
Microglia [52]

*Expression of these miRNAs has been reported for microglia of the brain.