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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Invest Dermatol. 2013 Mar 25;133(11):2530–2537. doi: 10.1038/jid.2013.151

Figure 5. CXCR4 and SOCS3 expression in human psoriatic skin.

Figure 5

Three human psoriasis skin samples containing the junctional zone between lesional and perilesional regions were biopsied (see Supplementary Table S1.). An example of H&E stainings showing these regions is shown (Patient 1; A). CXCR4 (B) and SOCS3 (C) stainings of the junctional and lesional area were performed and representative images of similar findings are depicted (Patient 2; See Supplementary Figure S6.). A healthy human skin sample was stained using anti-CXCR4 Ab (B; lower-left panel). CXCR4- and SOCS3-positive areas of 3 psoriasis patients were quantified using imageJ software and used for calculation of ratio (%) of marker-positive area to epidermal junctional or lesional zone areas (Right panels of B and C). Scale bars, 100 μm.