Table 2.
Baseline individual trabecular structural (ITS) analysis and their % changes (mean±SD) after 12 days of treatment over baseline.
| Baseline | % Changes in 12 days over baseline | ||||
|---|---|---|---|---|---|
| VEH | ALN | PTH | PTH+ALN | ||
| pBV/TV | 0.22±0.07 | 6.9±11.8 % | 20.8±7.8 % | 42.1±20.6 % | 73.3±33.6 % |
| rBV/TV | 0.091±0.012 | 4.0±14.8 % | −4.5±5.2 % | 10.8±7.6 % | −4.8±15.2 % |
| pTb.Th (mm) | 0.060±0.004 | 5.9±5.0 % | 5.7±1.7 % | 21.2±4.9 % | 20.5±8.6 % |
| rTb.Th (mm) | 0.051±0.003 | 3.5±3.7 % | 2.5±1.2 % | 9.0±6.0 % | 9.1±4.8 % |
| P-R Ratio | 2.4±0.8 | 5.3±24.3 % | 27.0±13.1% | 28.0±13.2 | 85.6±45.5 |
| pTb.N | 6.5±0.5 | −1.0±2.2 % | 2.4±1.4 % | 0.5±4.2 % | 5.9±5.1 % |
| rTb.N | 6.0±0.3 | −1.5±6.7 % | −3.4±2.2 % | −3.8±4.3 % | −8.4±6.0 % |
Significant % changes over baseline are given in bold. Baseline measures are from pooled data of all treatment groups. All parameters were not significantly different among treatment groups at baseline.