Table 2.
Results
| Group 1 (no growth factor) | Group 2 (rhBMP-2) | Group 3 (rhBMP2+VEFG) | |
|---|---|---|---|
| Capilarity density (%) | 13.35 (+/- 6.73) | 18.98 (+/- 9.71) | 32.13 (+/- 13.99) |
| Cortical blood flow (ml/min/100 g) | 0.12 (+/- 0.06) | 0.15 (+/- 0.08) | 0.25 (+/- 0.11) |
| Single label/bone surface (SLS/BS) | 5.56 (+/- 2.87) | 4.98 (+/- 2.61) | 5.23 (+/- 2.94) |
| Double label/bone surface (DLS/BS) | 3.82 (+/- 2.99) | 9.15 (+/- 7.42) | 10.15 (+/- 8.55) |
| Mineralized surface/bone surface (MS/BS;%) | 6.59 (+/- 2.30) | 11.64 (+/- 6.90) | 12.77 (+/- 8.14) |
| Mineral apposition rate (MAR;mm/day) | 6.60 (+/- 2.30) | 11.64 (+/- 6.90) | 12.77 (+/- 8.14) |
| Bone formation rate/bone surface (BFR/BS;mm3/mm2/year) | 24.78 (+/- 19.63) | 73.32 (+/- 75.32) | 93.47 (+/- 91.17) |
| Bone volume/total volume (BV/TV) | 62 (+/- 9.7) | 63 (+/- 9.8) | 65 (+/- 8.5) |
| Bone surface/bone volume (BS/BV; mm/mm2) | 4.73 (+/- 2.51) | 4.95 (+/- 1.79) | 4.44 (+/- 2.36) |
| Osteocyte-filled lacunae (%) | 57.37 (+/- 8.55) | 60.45 (+/- 8.55) | 61.34 (+/- 8.89) |
| Osteoblast count (N cells)* | 22.93 (+/- 8.14) | 26.00 (+/- 9.23) | 41.44 (+/- 19.22) |
| Osteoclast count (N cells)* | 10.73 (+/- 3.41) | 11.8 (+/- 3.45) | 11.8 (+/- 2.64) |
3 fields at 400 × magnification.