Table 1. Demographic and clinical characteristics.
| Parametera | CrCL <30 ml/min (n=12) | CrCL 30–60 ml/min (n=12) | CrCL >60 ml/min (n=13) |
|---|---|---|---|
| Age (year) | 58.3 (11.2) | 70.0 (8.2) | 58.8 (11.4) |
| Sex (n (%)) | |||
| Male | 7 (58.3) | 10 (83.3) | 8 (61.5) |
| Female | 5 (41.7) | 2 (16.7) | 5 (38.5) |
| Race (n (%)) | |||
| White | 10 (83.3) | 11 (91.7) | 13 (100) |
| Black | 2 (16.7) | 1 (8.3) | 0 (0) |
| Ethnicity (n (%)) | |||
| Hispanic/Latino | 5 (41.7) | 10 (83.3) | 5 (38.5) |
| Non-Hispanic/Latino | 7 (58.3) | 2 (16.7) | 8 (61.5) |
| Weight (kg) | 76.5 (15.1) | 71.9 (11.5) | 76.3 (11.5) |
| Height (cm) | 170.3 (7.7) | 165.5 (8.5) | 173.2 (9.9) |
| BMI (kg/m2) | 26.4 (5.3) | 26.1 (2.5) | 25.4 (3.3) |
| CrCL (ml/min) | 20.6 (6.4) | 49.6 (7.3) | 95.8 (17.5) |
| Serum sodium (mmol/l) | 138.8 (3.2) | 140.3 (2.5) | 140.5 (1.4) |
| Serum osmolality (mOsm/kg) | 315.1 (11.4) | 297.7 (8.6) | 292.6 (3.6) |
| Serum creatinine (mg/dl) | 3.5 (1.0) | 1.5 (0.3) | 0.9 (0.2) |
| Cystatin C (mg/l) | 3.4 (0.7) | 1.3 (0.3) | 0.9 (0.3) |
Abbreviations: BMI, body mass index; CrCL, creatinine clearance.
a
All values presented as mean (±s.d.), unless otherwise specified.