Table 3.
Migraine and Obesity in Peri- and Post-Reproductive-Aged Participants
| Reference | Study Design/Name | Sample Size | Sex | Age Range | Obesity DX | HA DX | Findings |
|---|---|---|---|---|---|---|---|
| Mattson (2007)8 | CS | Total: 684 EM: 130 |
Women only | 40–74 years | Measured TBO | ICHD | In older women, neither migraine prevalence or migraine attack frequency was associated w/total body obesity, using measured body mass indices (BMI-m). |
| Winter et al (2009)9 | CS/WHS | Total: 63,467 EM: 9195 |
Women only | ≥45 years | Self-reported TBO | Non-ICHD | In older women, there was no association between total body obesity (BMI-sr) and active migraine or prior history of migraine. |
| Peterlin et al (2010)5 | CS/NHANES | Total: 6152 (>55 years) EM: 749 |
Both sexes separately | ≥55 years | Measured TBO and Abd-OB | Non-ICHD | In older men, the odds of migraine were not associated with total body obesity (BMI-m) or abdominal obesity (WC). In older women, the odds of migraine were not associated with total body obesity (BMI-m). In older women, the odds of migraine were decreased in those with abdominal obesity (WC). |
Abd-OB = abdominal obesity; AMPP = American Migraine Prevalence and Prevention; BMI-sr = body mass index based on self-report; BMI-m = body mass index based on measured height and weight; CDH = chronic daily headache; CS = cross-sectional; DX = diagnosis; EH = episodic headache; EM = episodic migraine; ICHD = International Classification of Headache Disorders; Long = longitudinal; NHANES = National Health and Nutrition Examination Survey; NL= normal; TBO = total body obesity; WC = waist circumference; WHR = waist to hip ratio; WHS = Women’s Health Study.