Figure 3.

Injection with pmhyGENIE-3-GL3 leads to sustained expression of luciferase protein. (A) Representative images from mice s.c. injected with liposomes alone (mock), pmhyGENIE-3-ΔPB-GL3, or integrating pmhyGENIE-3-GL3 and luciferase activity monitored over time using an IVIS imaging system. (B) Data are shown for Days 1, 14 and 28 post-injection and represent mean + S.E.M. (N = 5/group). Means were compared using a student’s t-test with significance at *P< 0.05.