Figure 2. see also Figures S2 and S3. Thirty-one genome-wide significant loci associated with metabolites in FHS.
Loci with significant metabolite associations in FHS are depicted within the black circle. Overlap with prior studies (dotted circles) is indicated for 8 loci. Prior studies found an association between common variants at *AGXT2 and urinary levels of β-aminoisobutyric acid, †GCKR and the alanine/glutamine ratio, and ‡SLC16A10 and the tyrosine/isoleucine and alanine/tyrosine ratios.