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. 2014 Mar 28;55(3):1910–1918. doi: 10.1167/iovs.14-13867

Figure 4.

Figure 4

Effect of light stress on RPE cells in superior retina of Abca4+/+ and Abca4−/− mice. (A–F) Numbers of RPE cells (mean ± SEM) counted within 0.2-mm intervals and plotted as function of distance from ONH in superior hemiretina at 2, 5, and 8 months of age in Abca4+/+ (A, C, E) and Abca4−/− mice (B, D, F). (G) Total numbers of RPE cells from ONH to 1.0 mm along vertical axis in superior hemisphere of light-stressed (right) and control non–light-stressed eyes of Abca4+/+ and Abca4−/− mice at 2, 5, and 8 months of age (mean ± SEM; means are based on three values). *P < 0.05 as compared to fellow control eye; paired t-test; **P < 0.05 light-stressed Abca4+/+ versus Abca4−/− mice; unpaired t-test.