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. 2014 Mar 13;5(3):e1111. doi: 10.1038/cddis.2014.56

Table 1. Mean phenothiazine-induced cytotoxicity across the lung cancer cell line panel.

Cell line Cytotoxicity (%) at 10μM
  cisFPX PZ CPZ TFPZ FPZ TFP Mean S.D.
SCLC
 H69 43 19 82 61 58 57 53 21
 H82 85 43 90 80 100 100 83 21
 H592 59 40 63 59 69 57 58 10
 U-1285 93 84 100 100 100 100 96 7
 U-1568 20 22 40 30 14 15 24 10
 U-1690 10 20 48 23 29 36 28 13
 U-1906 50 50 95 93 76 74 73 20
 U-2020 75 49 89 85 94 96 81 18
                 
NSCLC
 A549 25 0 12 0 6 2 8 10
 H125 9 44 43 43 0 0 23 22
 H1299 0 3 52 13 0 0 11 21
 H157 44 25 30 33 37 44 36 8
 H23 1 8 17 5 7 8 8 5
 H661 20 21 29 13 19 10 19 7
 U-1752 32 37 40 28 31 32 33 4
 U-1810 28 14 23 9 20 9 17 8

The cytotoxicity values were calculated by the following formula: cytotoxicity=100%−viability (%), as analyzed by MTT assay