ISC improves hepatocytes proliferation and attenuates oxidative stress. Mitotic index (a), percentage of BrdU-positive hepatocytes (b) and PCNA protein levels (c) were measured at the indicated times. Densitometric analysis of the western blot results of PCNA (d) was performed 18, 21, 24 and 48 h post hepatectomy. Hepatic ATP content (e), ALT levels (f), damage score (g) and LDH (h), hepatic MDA levels (i), superoxide dismutase (j) and catalase (k) activities were measured at the indicated times. HSC70 served as a loading control. NL, normal liver. *P<0.05 versus SHAM, +P<0.05 versus PH, #P<0.05 versus NCPH and $P<0.05 versus TCPH (N=5)