Skip to main content
. 2014 Mar 6;5(3):e1107. doi: 10.1038/cddis.2014.65

Figure 6.

Figure 6

ISC attenuates the execution of ER stress and induces survival signaling through MAPK activation. GADD34, ASNS and EDEM mRNA expressions (a) were analyzed 3 and 24 h post hepatectomy. Phosphorylated-JNK1/2, p38 and ERK1/2 (b), caspase 12, cleaved caspases 9 and 3 (c) and cytosolic or mitochondrial cytochrome c (d) expressions were evaluated by western blot at the indicated times. Caspase 3 activity (e) was determined at the indicated times. *P<0.05 versus SHAM, +P<0.05 versus PH, #P<0.05 versus NCPH and $P<0.05 versus TCPH (N=5)