Table 1. The GI50 for each compound and M4 on the human lung cancer H460 and H460/TaxR cellsa.
Compounds/Cell lines | GI50/H460 (μM) | GI50/H460/TaxR (μM) | GI50/H460/TaxR in the presence of Reversan |
---|---|---|---|
27 | 0.46±0.01 | 0.56±0.01 | 0.37±0.03 |
107 | 1.45±0.22 | 1.75±0.07 | 0.86±0.18 |
167 | 0.99±0.01 | 1.19±0.03 | 0.95±0.004 |
254 | 0.52±0.01 | 0.58±0.001 | 0.56±0.004 |
M4 | 0.20±0.003 | 0.17±0.001 | 0.34±0.06 |
Taxol | 6.2±2.4 nM | 252±3.7 nM | 14.0±0.9 nM |
Data are expressed as mean±S.D. from three independent experiments