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. 2014 Mar 6;5(3):e1105. doi: 10.1038/cddis.2014.80

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Copyright © 2014 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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CsA promotes RGC survival in ischemic retina. Vehicle or CsA treatment was begun daily until 1 day before the induction of transient retinal ischemia and continued for 2 weeks. (a) Brn3a whole-mount immunohistochemistry. High magnification showed representative images from the central, middle and peripheral area of retinas. (b) Quantitative analysis of RGC survival. Values are mean±S.D. (n=7 retinas per group). *Significant at P<0.05 compared with vehicle-treated non-ischemic contralateral control retina and **significant at P<0.01 compared with vehicle-treated ischemic retina. Scale bar, 50 μm (all panels)